2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Drug Metabolite

Drug Metabolite

Drug Metabolite

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Drug metabolite results when a drug is metabolized into a modified form which continues to produce effects. Drug metabolism redox reactions such as heteroatom dealkylations, hydroxylations, heteroatom oxygenations, reductions, and dehydrogenations can yield active metabolites, and in rare cases even conjugation reactions can yield an active metabolite.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-W779504
    b-Cortolone
    b-Cortolone is the metabolite of Cortisol (HY-N0583), that reveals relatively low biological activity.
    b-Cortolone
  • HY-137546
    Reduced Haloperidol
    Reduced Haloperidol (Haloperidol metabolite II) is an antipsychotic compound with neurotransmitter modulating activity. Reduced Haloperidol is commonly used to inhibit schizophrenia and other psychotic disorders. Reduced Haloperidol helps reduce the occurrence of hallucinations and delusions by inhibiting the activity of dopamine receptors.
    Reduced Haloperidol
  • HY-113864
    Diisobutyl carbinol
    Diisobutyl carbinol (DIBC) is an orally active organic solvent widely used as industrial intermediates and fragrance ingredient. Diisobutyl carbinol and Diisobutyl ketone are well interconverted metabolically in rats.
    Diisobutyl carbinol
  • HY-135389R
    Desmethyl Levofloxacin (Standard)
    Desmethyl Levofloxacin (Standard) is the analytical standard of Desmethyl Levofloxacin. This product is intended for research and analytical applications. Desmethyl Levofloxacin is a metabolite of Levofloxacin. Levofloxacin, a synthetic fluoroquinolone, is an antibacterial agent that inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.
    Desmethyl Levofloxacin (Standard)
  • HY-169828
    Ketopynalin
    Ketopynalin (CGP-85903) is a metabolite of Vatalanib (HY-10203).
    Ketopynalin
  • HY-137522AS1
    Zidovudine Glucuronide-13C6
    Zidovudine Glucuronide-13C6 (3'-Azido-3'-deoxythymidine β-D-glucuronide-13C6) is 13C labeled Zidovudine O-β-D-glucuronide. Zidovudine O-β-D-glucuronide (3'-Azido-3'-deoxythymidine β-D-glucuronide) sodium is the major metabolite of Zidovudine. Zidovudine is a nucleoside reverse transcriptase inhibitor (NRTI), widely used to treat HIV infection.
    Zidovudine Glucuronide-<sup>13</sup>C<sub>6</sub>
  • HY-136457R
    2-NP-AHD (Standard)
    2-NP-AHD (Standard) is the analytical standard of 2-NP-AHD. This product is intended for research and analytical applications. 2-NP-AHD is a 2-nitrophenyl derivative of AHD (a metabolite of nitrofurans type of antibiotics), can be used as indicator of the illegal usage of nitrofuran agents.
    2-NP-AHD (Standard)
  • HY-W209596
    N-Acetylglyphosate
    N-Acetylglyphosate is a metabolite of the pesticide Glyphosphate.
    N-Acetylglyphosate
  • HY-I0777R
    1,2-Diacetylhydrazine (Standard)
    Acetic acid, 2-acetylhydrazide (Standard) is the analytical standard of Acetic acid, 2-acetylhydrazide. This product is intended for research and analytical applications.
    1,2-Diacetylhydrazine (Standard)
  • HY-W714238
    Spirotetramat-mono-hydroxy
    Spirotetramat-mono-hydroxy is a metabolite of Spirotetramat (HY-120253). Spirotetramat is an insecticide.
    Spirotetramat-mono-hydroxy
  • HY-168799
    3-Methoxy prostaglandin F1α
    3-Methoxy prostaglandin F1α is an analog of PGF1α that can be metabolized by naturally occurring extracellular antibiotic resistance genes (eARGs) that enter the intestine via the food chain.
    3-Methoxy prostaglandin F1α
  • HY-186081
    Ramiprilat acyl-β-D-glucuronide
    Ramiprilat acyl-β-D-glucuronide is an acyl glucuronide metabolite of Ramiprilat (HY-B0279). Ramiprilat acyl-β-D-glucuronide undergoes methylation on its glucuronic acid moiety during solid phase extraction with strong cation exchanger cartridges, forming a methylated derivative. Ramiprilat acyl-β-D-glucuronide undergoes in-source conversion to Ramiprilat in mass spectrometry, with conversion extent proportional to declustering potential voltage.
    Ramiprilat acyl-β-D-glucuronide
  • HY-113043
    Galactonic acid
    Galactonic acid is a metabolite of Galactose. Galactose is converted into Galactonic acid in vivo. Galactonic acid can be used in galactosemia research.
    Galactonic acid
  • HY-129708
    LU 2443
    LU 2443 is an orally active antiepileptic mesoionic. LU 2443 is extensively absorbed, in the maximum 18% are eliminated unabsorbed in rats. The half-time of the activity in plasma is 13.17 h.
    LU 2443
  • HY-B0277R
    Vidarabine (Standard)
    Vidarabine (Ara-A) (Standard) is the analytical standard of Vidarabine. This product is intended for research and analytical applications. Vidarabine is a nucleoside antibiotic isolated from Streptomyces, and a metabolite of Vidarabine phosphate (HY-B0277A). Vidarabine selectively inhibits viral DNA polymerase and cellular ribonucleotide reductase, thereby blocking viral replication. Vidarabine phosphate also exhibits antifungal activity, induces late-stage cellular apoptosis, and causes cell cycle arrest. Vidarabine phosphate can be used in research related to severe chronic active Epstein-Barr virus (EBV) infection, herpes infection, and candidiasis.
    Vidarabine (Standard)
  • HY-141410
    Fluticasone dimer impurity
    Fluticasone dimer impurity is a dimeric impurity of Fluticasone Propionate. Fluticasone propionate is a corticosteroid with comparatively high receptor affinity and topical activity.
    Fluticasone dimer impurity
  • HY-170629
    3,4-DMMC metabolite hydrochloride
    3,4-DMMC metabolite hydrochloride is a metabolite of 3,4-Dimethylmethdrug derivative. 3,4-Dimethylmethcathinone is a stimulant agent.
    3,4-DMMC metabolite hydrochloride
  • HY-168367
    2-Hydroxyethylflurazepam
    2-Hydroxyethylflurazepam (compound II) is a metabolite of Flurazepam.
    2-Hydroxyethylflurazepam
  • HY-100642
    3-O-Methyltolcapone
    		99.95%
    3-O-Methyltolcapone (Ro 40-7591) is a metabolite of Tolcapone (HY-17406). Tolcapone (Ro 40-7592) is a selective, potent and orally active COMT inhibitor with an IC50of 773 nM. Tolcapone can inhibits α-syn and Aβ42 oligomerization and fibrillogenesis. Tolcapone can cause oxidative stress and induce cancer cells apoptosis and ROS production. Tolcapone can be used for the researches of cancer and neurological disease, such as Parkinson disease and neuroblastoma.
    3-O-Methyltolcapone
  • HY-W012982R
    3-Amino-2-oxazolidinone (Standard)
    3-Amino-2-oxazolidinone (Standard) (AOZ (Standard)) is the analytical standard of 3-Amino-2-oxazolidinone (HY-W012982). This product is intended for research and analytical applications. 3-Amino-2-oxazolidinone (AOZ) is the metabolite of Furazolidone (HY-B1336). 3-Amino-2-oxazolidinone is always be detected as a indicator of furazolidone residues in vivo. 3-Amino-2-oxazolidinone is orally active.
    3-Amino-2-oxazolidinone (Standard)
Cat. No. Product Name / Synonyms Application Reactivity